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Webinar: Chromatographic Clarification for Problematic Host Cell Protein Removal

August 27 @ 10:00 am - 11:00 am MDT

In Hani’s two-part webinar series, he will share data from recent research collaborations with University College London (UCL) and The National Institute of Bioprocessing Research and Training (NIBRT), exploring the impact of applying flow-through chromatography with nonwovens on clearance of soluble impurities, particularly Host Cell DNA. The research begins by investigating the impact of DNA removal prior to Protein A chromatography on the clearance of key problematic host cell proteins tracked using sophisticated LC-MS techniques. It will then show how DNA clearance during clarification can enhance the performance of Continuous Protein A Capture Chromatography. Building on the earlier webinars, these webinars are intended for new and experienced Process Development Scientists alike.