Mammalian cell culture continues to be the workhorse for the expression of high-value therapeutic recombinant protein modalities. As requirements for manufacturing process performance, product quality and process safety become more stringent, cell shear during clarification has become a critical consideration for both preventing product degradation and designing clarification processes. In this webinar, Masa will present on cell shear mechanisms during clarification, the impact of cell shear on product quality and strategies to mitigate cell shear in depth filtration.