Videos

In this third installment, Dr Aditya Bhat and Dr Sven Ansorge discuss the usefulness of capacitance measurement in Viral Vector-vaccine production processes, highlighting Sven's work and pieces of research for this pertinent topic considering the current Covid-19 pandemic and also looking at the adoption of capacitance in cGMP manufacturing with reference to the useful papers produced by Biogen in recent years. Learn More

ABEC is inviting you on a live guided tour through their CSR® Single-Use Process area, CSR Disposable Container (DC) Manufacturing ISO-7 clean rooms, and the bioprocess equipment manufacturing floors of their USA & Ireland Facilities. Learn More

In Part 2 of this 3 Part series, Dr Aditya Bhat and Dr Sven Ansorge take a closer look at the speed of adoption of capacitance for measuring biomass in-line compared to other parameters and the impact of the FDA's PAT initiative on accelerating the adoption of capacitance as a really useful tool in manufacturing. Learn More

This video, produced by AdvantaPure, shows the burst, leak/integrity and vacuum testing of their AdvantaSil™ High Pressure Silicone Tubing by the development team. Learn More

This video, produced by PDA, features a brief discussion with Kevin Jenkins, Pfizer (now retired), about how to conduct an effective deviations investigation.

This video, produced by PDA, features a brief discussion with Amgen's  Chakradhar Padala, Director of Process Development, on  the latest advancements in Aseptic Processing.

Andrew Hessel is a futurist and catalyst in biological technologies, helping industry, academics, and authorities better understand the changes ahead in life science. He is a Distinguished Researcher with Autodesk Inc. Bio/Nano Programmable Matter group, based out of San Francisco. He is also the co-founder of the Pink Army Cooperative, the world first cooperative biotechnology company, which is aiming to make open source viral therapies for cancer.

This video, produced by AdvantaPure, explains the features and benefits of their highly validated AdvantaFlex TPE Tubing.

This video, produced by G-Con, tells the story of how prefabricated PODs were delivered in 8 months to Rubius Therapeutics' cGMP facility in Smithfield, Rhode Island. Meeting their aggressive timeline and providing speed to market for clinical manufacturing.

This video, produced by Hamilton Process Analytics, illustrates how traditional pH sensor management in a production process is costly and labor intensive - the cost of the sensor only accounts for 20 percent of total operational cost.

This video, produced by IDEX Health & Science, discusses real-time antibody titer monitoring for bioprocessing using their Tridex protein analyzer.

This video, produced by Hamilton Process Analytics, utilizes narration and animation to provide insights into the basics of pH measurement.

This video, produced by Sartorius, provides practical advice for those trying to develop and implement continuous processes. It explains the tools and techniques that can be used during process development and describe how process-scale equipment can be configured to allow effective and predictable scale-up.

This video, which has 120,000+ views, describes the process by which a biological product-in this case, a pure, concentrated solution of Green Fluorescent Protein (GFP)-is derived from clarified lysate.  This is accomplished through multiple variations of two basic procedures: chromatography and filtration.

This video, which has 100,000+ views, describes the process by which a biological product-in this case, molecules of Green Fluorescent Protein (GFP)-is recovered from host e coli cells.  The steps of this process are, in very basic terms: (1) separation of cell solids from the broth, (2) disruption of those host cells to release the product contained in them, and (3) isolation of the product through removal of cell debris and other impurities.  Tools used to perform these steps include centrifuges, cell disrupters and microfilters.

This video, which has 300,000+ views, describes the role of the fermentation process in the creation of biological products and illustrates commercial-scale fermentation at a cellular level.  Included are descriptions of types of fermentation; intracellular, extracellular, types of cells (aerobic, anaerobic), and cell nutrition/media.

In this video, produced by OSIsoft, Poul Waagner Nielsen, Project Manager, Manufacturing Intelligence, at LEO Pharma describes using the PI System as a central warehouse of production data for the people and manufacturing systems in their six factories spread across Europe. Learn More

This video, produced by OSIsoft, features a brief discussion with Patrick T. O' Sullivan, Data Science Lead at Janssen in Cork, Ireland. During which he shares how Janssen is using the PI System to reduce the amount of time they spend doing data prep for their multi-million data point systems.

This video, which has 170,000+ views, utilizes a combination of animation and narration to explain the basics of Raman spectroscopy and the principles associated with application of the technology.

This video, produced by Saint-Gobain, explains the three steps commonly associated with the validation process; Installation Qualification (IQ), Operation Qualification (OQ) and Performance Qualification (PQ). These processes, when combined, usually make up the foundation of a validation package.

This video, produced by Saint-Gobain, provides a concise definition of the practice of validation accompanied by a well-informed explanation that expands on the definition to provide an improved understanding to the associated principles and practices.

This video, which has 345,000+ views, explains the measurement principles behind the four most common approaches to the measurement of liquid flow; Mechanical, Magnetic, Vortex and Ultrasonic.

This video, which has 40,000+ views, uses a combination of illustration and narration to explains the principles and practices associated with gel electrophoresis.

This video features an interview with Erik Klijn, Senior Data Analytics Lead, at Janssen. During which he discusses the deployment of an OSIsoft PI system to conduct advanced analytics in biopharma manufacturing. This includes an application where the PI system is used to analyze the impact of raw materials on bioreactor performance.

This video, which has 8,000+ views, reviews the 3 pillars for maintaining a validated state. Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ).

This video, which has 5,000+ views, was produced by the U.S. FDA to explain the concept of interchangeability. The video features an interview with Leah Christl, Ph.D., former Associate Director for Therapeutic Biologics and lead of the Office of New Drugs (OND) Therapeutic Biologics and Biosimilars staff at FDA CDER.

This video, which has 10,000+ views, was produced by the U.S. FDA to address the question of "What are biosimilar products?" The video features an interview with Leah Christl, Ph.D., former Associate Director for Therapeutic Biologics and lead of the Office of New Drugs (OND) Therapeutic Biologics and Biosimilars staff at FDA CDER.

This video, which has 50,000+ views, was produced by the US FDA and uses animation supported by narration to provide an introduction to the practice of gene therapy.

This video, which has 5,000+ views, explains the functionality of a rotary pump by utilizing a narrated animation to demonstrate its operation.

This video discusses the basic principles for selecting an appropriate impeller for blending fluids in a stirred tank is an excerpt from the AIChE Academy eLearning Course "Fluid Mixing Technology for Operators".

This video, which has 18,000+ views, demonstrates how to prepare an ultralight foam from cross linked gelatin, which can be used to keep cells alive for up to a week at room temperature. No incubator, CO2, dry ice or liquid nitrogen required.  The material is easy to make and prepare and the method works for both adherent and suspension cells.

This video, which has 25,000+ views, uses animation and narration to  explain the measuring principle of Pt100 thin-film sensors. It also provides hints for installation in the process and describes the evaluation of the signals using temperature transmitters and displays.

This video explains the differences between the two most common  curing methods of silicone tubing; platinum curing and peroxide curing. In so it provides the viewer with an improved understanding of the advantages and challenges to be found with each.

This video, which has 18,000 views, describes the various pressure relief solutions available to protect operators and process equipment alike.

This video by Mettler Toledo, which has 9,500+ views, shares the  three things you really should know about the recommendations  made in USP 41 for achieving good weighing practices.

This video, which as 12,000+ views, utilizes a series of highly informative slides to explain the principles and practices associated with upstream bioprocessing aspects of fermentation.

This video, which has 10,000+ views, explains the role of cell therapy and that which differentiates it from the other therapeutics.

This video, which has 40,000+ views, explains through a narrated illustration the principle of measuring level with vibration.

This video, which has 35,000+ views, explains how the oxygen concentration in a liquid can be measured using the amperometric or optical measurement principles.

This video, which has 80,000+ views, uses narration and illustration to explain how a pH electrode and meter work together to measure pH.

This video, which documents a Gene Therapy site build, provides insight into the role modular/prefabricated facilities are playing in the advancement of our industry.

This video, which has 40,000+ views, provides a helpful introduction to the principles and practices associated with measuring flow with a Coriolis meter.

This video, which has 165,000+ views, provides a narrated demonstration of proper procedure for cleanroom gowning in bioprocessing.

This video, which has 80,000+ views, explains the role of clinical trials in drug discovery.

This video, part 2 of 6, provides an introduction to the principles and practices associated with viral safety.

This video, part 1 of 6, provides an introduction to the principles and practices associated with viral safety.

This animated video, which has 295,000+ views, provides an explanation of normal phase vs reverse phase HPLC. Please note that while highly informative, there is no audio.

This video, which has 19,000+ views,  demonstrates why you cannot use geometric scale-up of a batch reactor with heat transfer.

This video, part 3 of a 4 part series, provides insights into the principles and practices associated with bioprocess validation.

This video, which has 160,000+ views, provides the principles and practices associated with aseptic gowning for work in a cleanroom.

This video provides insight into the reality of viral contamination and serves as an introduction to the principles and practices associated with viral safety.

This video, which has 20,000+ views, explains cell culture media and the components of culture media for cell growth.