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Career Center | Aspen Xchange
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Pros and Cons: Working in Small Life Sciences Companies vs. Large Organizations

Is your dream job with a large organization or a small company? It’s common for life sciences professionals to have a preference one way or the other when considering employment opportunities. While many people might have a primary reason for desiring to work at a small company or a large organization, most individuals haven’t really compared the differences and the implications on their career. Are you impressed by large established organizations? Or, do you seek out innovative start-ups and small companies? To help with your career planning, we’ve compiled a list of the major pros and cons when working in small companies versus large organizations!

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A Comparative Review of Multi-Rate Moving Horizon Estimation Schemes for Bioprocess Applications

Advanced control and monitoring of bioprocesses are dependent on accurate state and parameter information. At the same time, bioprocesses are well known for their time-varying behavior and difficulty of obtaining online measurements of the important process states. The selection and the tuning of the estimation algorithms is therefore crucial to the design of reliable monitoring tools. In this work we discuss the design of several Moving Horizon Estimation schemes for a class of bioprocesses. We compare the algorithms in terms of the arrival cost computation and address the implementation of a multi-rate measurement structure. The tuning of the estimators and further details are illustrated using a cell culture case study, where we show that not all the estimators under investigation can cope equally well with process uncertainty and multi-rate measurements.
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Two Biotech Firms Investing Total of $228 Million to Build Facilities in Puerto Rico

CytoImmune Therapeutics and Biosimilar Sciences have made public plans to establish operations in Puerto Rico to develop their biotechnology products. For its part CytoImmune Therapeutics will invest $28 million for a facility to engage in developing cancer immunotherapy solutions. While Biosimilar Sciences will invest $200 million to establish a state-of-the-art biotech facility for the development of biosimilar products, including a COVID-19 vaccine, new cell and gene therapy, biologics, clinical studies, and other recombinant biotechnologies.
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