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Pros and Cons: Working in Small Life Sciences Companies vs. Large Organizations

Is your dream job with a large organization or a small company? It’s common for life sciences professionals to have a preference one way or the other when considering employment opportunities. While many people might have a primary reason for desiring to work at a small company or a large organization, most individuals haven’t really compared the differences and the implications on their career. Are you impressed by large established organizations? Or, do you seek out innovative start-ups and small companies? To help with your career planning, we’ve compiled a list of the major pros and cons when working in small companies versus large organizations!

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Developing a Computational Framework to Advance Bioprocess Scale-Up

Bioprocess scale-up is a critical step in process development. However, loss of production performance upon scaling-up, including reduced titer, yield, or productivity, has often been observed, hindering the commercialization of biotech innovations. Recent developments in scale-down studies assisted by computational fluid dynamics (CFD) and powerful stimulus-response metabolic models afford better process prediction and evaluation, enabling faster scale-up with minimal losses. In the future, an ideal bioprocess design would be guided by an in silico model that integrates cellular physiology (spatiotemporal multiscale cellular models) and fluid dynamics (CFD models). Learn More

Thermo Fisher Plans $130 Million Sterile Filling Plant in Singapore

Thermo Fisher Scientific has announced plans to build a $130 million sterile filling plant in Singapore, extending its capacity to develop and manufacture therapies and vaccines to the Asia-Pacific region. The plant, when operational in 2022, will have the capacity to make up to 30 million sterile doses a month and employ more than 300 people. Thermo Fisher said the new plant will initially include a high-speed sterile line approved for live virus filling, followed by an additional line for standard fill/finish. The facility will also have cleanroom capacity, labs, warehousing and offices to support production, the company said. Learn More