In a major collaborative effort, researchers at the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) have for the first time eliminated replication-competent HIV-1 DNA — the virus responsible for AIDS — from the genomes of living animals. The study, reported online July 2 in the journal Nature Communications, marks a critical step toward the development of a possible cure for human HIV infection. For the new study, Dr. Khalili and colleagues combined their CRISPR-CAS 9gene editing system with a recently developed therapeutic strategy known as long-acting slow-effective release (LASER) ART. Learn More