A U.S. Patent Application for a “Method of Producing a Recombinant Protein” was published by GSK on June 13th, 2019. The present invention relates to a recombinant signal sequence, and a fusion protein comprising the signal sequence and a recombinant protein. Methods of producing the recombinant protein using the recombinant signal sequence are described. In particular, the recombinant signal sequence provides a method for controlling the viscosity of the fermentation, and/or controlling basal (pre-induction) expression of the recombinant protein. Learn More