Cell Culture Additives and Their Use for Increased Bioprotein Production from Cells



A U.S. Patent for ” Cell Culture Additives and Their Use for Increased Bioprotein Production from Cells”  was awarded to Air Liquide  on May 7th, 2019. The present invention relates to a method of increasing protein biomolecule production in which a) a cell that produces a heterologous protein biomolecule is cultured, and b) an Additive and/or a source of the Additive is added to the culture medium in an amount sufficient to (i) increase a total yield of the heterologous protein biomolecule secreted into the cell culture media and/or (ii) increase a specific cellular productivity of the heterologous protein biomolecule secreted into the cell culture media. Learn More