Production of Extracellular Vesicles in Single-Cell Suspension Using Chemically-Defined Cell Culture Media



A U.S. Patent Application for “Production of Extracellular Vesicles in Single-Cell Suspension Using Chemically-Defined Cell Culture Media” was published by Codiak BioSciences on March 21st, 2019. The present invention are methods for the production of extracellular vesicles comprising culturing a population of producer cells in single-cell suspension, wherein the cells are cultured in chemically-defined culture medium, wherein the culture medium lacks animal-derived serum and animal-derived components; and obtaining from the cell culture an extracellular vesicle preparation comprising extracellular vesicles. Learn More