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Pilot‐Scale Demonstration of an End‐to‐End Integrated and Continuous Biomanufacturing Process | Aspen Xchange
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Pilot‐Scale Demonstration of an End‐to‐End Integrated and Continuous Biomanufacturing Process



There has been increasing momentum recently in the biopharmaceutical industry to transition from traditional batch processes to next‐generation integrated and continuous biomanufacturing. This transition from batch to continuous is expected to offer several advantages which, taken together, could significantly improve access to biologics drugs for patients. Despite this recent momentum, there has not been a commercial implementation of a continuous bioprocess reported in the literature. In this study, we describe a successful pilot‐scale proof‐of‐concept demonstration of an end‐to‐end integrated and continuous bioprocess for the production of a monoclonal antibody.
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