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High Density Fill and Draw Fermentation Process | Aspen Xchange
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A U.S. Patent for a “High Density Fill and Draw Fermentation Process” was awarded to CMC Biologics on November 24th, 2020. The present invention relates to a high cell density fermentation fill and draw process for producing a product in a bioreactor system wherein during the fermentation, medium comprising impurities is removed via the impurity filter unit while new fresh medium is added to the cell culture vessel to replenish consumed nutrients and expelled medium.
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