Bioreactors are a space-efficient method of growing cells en masse for industrial operations by suspending the cells in an agitated vessel full of cell culture media. Adherent cell lines can be grown on microcarriers in bioreactors to reduce the space needed for petri dishes or flasks in the lab. One of the important factors in cell culture is changing the cell media to remove cell waste, secreted products, and/or replenish the nutrients available. Bioreactors face unique challenges with media changes, as cells should not be removed from a culture when media is changed. Currently, some labs let the cells settle to the bottom of the bioreactor for 30-45 min before decanting the spent media and refilling the tank with new media. This project provides bioreactor users with three single-use products that separate microcarriers from media in a continuous flow, to shorten the time adherent cells are outside of their ideal environment. Learn More