Validated Quantitation and Activity Assay of Antibody Fragment Molecule (Fab) for Process Development and Quality Control

In this application note, published by ForteBio, the analytical group at Boehringer Ingelheim, Fremont, USA illustrates how they needed a robust assay to measure the biological activity of an antibody fragment (Fab) molecule for in-process testing as well as stability and lot release testing in their Quality Control (QC) department. The group was able to develop a working Fab activity assay on the Octet® RED system in less than a week. Learn More