The economically competitive bioproduction of specialty chemicals using microbial cultures often demands the use of complex feedstocks that have undergone minimal processing and purification. Such feedstocks may be high in cellulosic content, have dark color, contain a wide mixture of particle sizes, and exhibit substantial batch-to-batch variation. The real-time monitoring of cell density (or cell biomass) is essential to maintaining the health of the microbial culture and for optimizing the yield of bioproducts, but has been a long-standing challenge within such complex feedstocks. Learn More