This case study, authored by AdvantaPure, illustrates the performance of their custom BioClosure systems for bulk drug substance. The primary objective of the customer was to develop a closed system that was leak proof under operating conditions and maintained container closure integrity during storage at -70oC. Additionally, the customer was concerned about foaming that occurred when filling the container. AdvantaPure’s engineering team worked with the customer to design a custom system for their production needs. Learn More