From Process Development to Scale-up: Facing the Challenges in Vaccine Upstream Bioprocessing



Driven by epidemic events and by governmental vaccination programs, there is a rising demand for development of new vaccines and the industry is growing at a double-digit rate. The vaccine industry is facing the challenge of developing new products to serve so far unmet needs and fulfilling the demands on dose numbers, both in an economically viable way.

Upstream bioprocessing is an important piece of the puzzle. High titer, robustness of the process, constant product quality, fast turn-around times, and scalability are some of the success factors. With a comprehensive portfolio of scalable bioreactor and fermentor systems, software, single-use bioreactors, and worldwide service, Eppendorf strives to support bioprocess engineers in tackling these challenges.

With this ebook we would like to share expert views and case studies on some of the hot topics in vaccine bioprocess development. We hope the information on viral vector production, continuous bioprocessing, and process scale-up will prove useful for your own development projects.

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