A U.S. Patent for “pH Responsive Mucoadhesive Polymeric Encapsulated Microorganisms” was awarded to MIT on February 4th, 2020. The present invention is a method of encapsulating microorganisms, or components thereof, for targeted enteric delivery to an animal host have been developed. In particular, the encapsulation provides a prolonged survival, extended retention and a pH-sensitive release of the encapsulated microorganisms or antigenic components thereof at targeted sites within the gastrointestinal tract. The formulations are useful for diagnostic, therapeutic and prophylactic purposes and can alter a host’s microbial composition associated with a condition or a disease state. Learn More