A U.S. Patent Application for “Methods of Selecting Subjects for Combination Cancer Therapy with a Polymer-Conjugated Soluble” was published by Halozyme on November 21st, 2019. The present invention are methods of selecting subjects having cancer for combination therapy that includes administering an anti-hyaluronan agent, such as a polymer-conjugated hyaluronan-degrading enzyme. Combination therapies can include, in addition to the anti-hyaluronan agent, a tumor-targeted taxane and, optionally, a chemotherapeutic agent such as a nucleoside analog. Combinations for performing the methods are provided, as are uses of the combinations for selecting subjects for treatment. Learn More