A U.S. Patent for “Antigen-Binding Molecule Capable of Binding Two or More Antigen Molecules Repeatedly” was awarded to Chugai on November 12th, 2019. The present invention is a method of removing an antigen from plasma, the method comprising: administering an antibody to an individual in need of having an antigen removed from the individual’s plasma, wherein the antibody binds to the antigen through the antigen-binding domain of the antibody and has a KD(pH5.8)/KD(pH7.4) value, defined as the ratio of KD for the antigen at pH 5.8 and KD for the antigen at pH 7.4, of 40 to 1,000, wherein the antibody binds to the antigen in plasma in vivo… Learn More