Thursday, October 24th, 2019

Accumulation of CO2 in fermentation and cell cultures can become a significant problem affecting productivity and product quality of recombinant proteins and monoclonal antibodies (mAbs). During this webinar, the following topics will be approached with a technical perspective:

  • Measuring CO2 inline and monitor its accumulation
  • Elevated CO2 partial pressure (pCO2) can alter protein glycosylation and affects the purity of mAbs.
  • pCO2 is affecting media and intracellular osmolality
  • Measuring pCO2 offline versus inline
  • Monitoring and controlling CO2 during a fermentation

A list of scientific references for fermentation and cell culture processes will be also communicated and available after the webinar.

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