There is a growing awareness regarding the potential leaching of toxic or inhibitory chemicals from the plastic material of single-use bioreactors into cell culture medium. Based on a standardized cell culture test recommended by the German society for chemical engineering and biotechnology, DECHEMA®, we determined if there were no leachable chemicals from the Eppendorf BioBLU Single-Use Vessel material that affect cell culture performance. We did not observe any effect of leachables on CHO and Vero cell growth and viability, and the metabolic profile. The results suggest that the BioBLU Single-Use Vessels are safe for mammalian cell culture.

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Original Publication Date: 11/01/2016