GE Healthcare has announced the opening of a biotechnology manufacturing center at the Stevenage Bioscience Catalyst (SBC) Open Innovation Campus, in Stevenage, UK. In the first half of 2019, the center will start producing a fiber-based purificat
The U.S. FDA this week approved Celltrion and Teva's Truxima as the first biosimilar to Rituxan. This is the FDA's 15th biosimilar approval overall, the third in the last month and the first for rituximab in the US. Only six biosimilars are curren
A U.S. Patent for a "Process for Protein Production" was awarded to Novo Nordisk on November 27th, 2018. The present invention relates to a process for the production of a haemostasis protein by continuous perfusi
Process for Protein Production
The U.S. FDA earlier this month confirmed the capabilities of Belgium, Denmark, Finland and Latvia so that the FDA can now rely on the inspections in each of those countries, reducing the need for duplicative work. A total of 19-member states in t
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Single use processing has become increasingly more prevalent in bio-manufacturing. While its use is prolific in cell culture, filtration, mixin
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The actress Natalie Wood, who starred in such movies as Rebel Without a Cause and West Side Story, drowned in a boating accident near California's Catalina Island. She was 43 years old.
1981 Natalie Wood drowns
Novartis has announced that it is moving its HQ in the United Kingdom from Surrey to White City in West London. The new HQ, consisting of roughly 54,000 sq. ft of space on the second floor of the WestWorks building, is part of the White City Place
Novartis Moving UK Headquarters to London
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Which best describes the opportunity for a biopharma start-up located outside a major hub like Cambridge or San Francisco? %
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Is it very important that people can use the internet without government censorship?
China is approving foreign drugs at a record pace, opening the door to its lucrative market for the world's leading pharmaceutical companies, while also extracting big discounts. Regulators have greenlighted dozens of outside drugs for use in Chin
Drugmakers Gain More Access to China, But at a Price
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For the introverts among us, traditional forms activism like marches, pr
Born in Seattle, Hendrix grew up playing guitar, imitating blues greats like Muddy Waters as well as early rockers. He's remembered for classic songs as Purple Haze, Foxy Lady, and The Wind Cries Mary.
In 2010, a Rice University graduate student named He Jiankui published a paper describing the nitty-gritty details of a then-arcane bacterial immune system called CRISPR. It was well before scientists unlocked the knowledge that CRISPR could be us
Researcher in China Claims to Have Made Genome Editing History
The U.S. FDA this week approved an advanced cancer treatment drug that combats solid tumors caused by a rare genetic mutation.The drug will be sold under the brand name Vitrakvi in a partnership between US-based pharmaceutical company Loxo Oncolog
The U.S. FDA has approved Pfizer's Daurismo for patients with acute myeloid leukemia (AML) who are over 75 or who can't take intensive chemotherapy, a particularly hard-to-treat population. The approval of once-daily oral Daurismo with low-dose ch
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Amgen - West Greenwich, RI
Process Development Scientist
It sounds like you saw the BIOne product from the folks at Distek. As you mention, it is a bag based solution that converts your classic glass bioreactor, 2L and 5L working volume, into a single-use solution by acting as a liner complete with a di
Do you know the name of the company that has the single-use bioreactor bag that fits inside a 3L glass bioreactor? I saw it at a recent conference but cannot find the company.
A U.S. Patent for "Devices, Systems and Methods for Automated Cell Culturing" was awarded to GE on November 20th, 2018. The present invention is a multi-scalable bioreactor, which comprises a culture vessel for se
Lonza has announced the opening of its new R&D center in Israel, named Israeli Collaborative Innovation Center (CIC). The Center, located in Haifa's Life Science Park, currently employs 15 researchers, focusing on molecular biology and molecul
Epigenetic therapies, those targeting enzymes that alter what genes are turned on or off in a cell, are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant. Researchers at Boston Children's Hospita
Perfusion processes typically require removal of a continuous or semi-continuous volume of cell culture in order to maintain a desired target cell density. For fast growing cell lines, the product loss from this stream can be upwards of 35%, signi
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The discovery by Howard Carter of Tutankhamun's nearly intact tomb received worldwide press coverage. It sparked a renewed public interest in ancient Egypt. Learn
BASF has unveiled a company-wide reorganization that will involve moving its 11 business units into six divisions. The company will also simplify structures and processes, sharpen its portfolio, and better align its businesses to its customers. As
J&J suffered a serious setback in court last week when the U.S. Court of Appeals for the Federal Circuit declined the biopharma giants request for a temporary restraining order. The order was being sought in an effort to prevent Mylan and othe
Rentschler Fill Solutions, a contract development and manufacturing organization (CDMO), has officially inaugurated its new state-of-the-art facility in Rankweil, Austria. In August, the company obtained the certificate of GMP compliance and the p
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Sun Pharma has made public plans to combine its manufacturing operations currently located in the New Jersey cities of New Brunswick and Cranbury, potentially costing nearly 100 workers their jobs. According to a federal WARN notice, the consolida
The Trump administration has accused the Chinese government of "unfairly" using venture capital to acquire cutting-edge technologies being developed in the United States, including biotechnology and artificial intelligence. In a report released th
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London was one of the first writers to become a worldwide celebrity and earn a large fortune for writing. His most famous works include The Call of the Wild and White Fang, both set in the Klondike Gold Rush.
The U.S. FDA has made official its concerns with Mylan's handling of operations at its largest manufacturing plant, issuing a sharply critical warning letter earlier this month that lays out a series of missteps and oversights at the Morgantown, W A 99-year lease was supposed to be the key to creating a $1.2 billion biotech village here, bringing thousands of jobs and millions in tax revenue. It was never signed. Westchester County lawmakers approved a deal in April 2017 with Fareri Associa In the DNA of Bacteria. Learn More A U.S. Patent for "Protein Purification Using Bis-Tris Buffer" was awarded to Sanofi on November 20th, 2018. The present invention is a method for purifying a monoclonal antibody or antigen-binding fragment thereo Vaccine maker Seqirus, a business unit of CSL, has broken ground on a $140 million expansion of its manufacturing site in Holly Springs, North Carolina. The Holly Springs plant, at 475 Green Oaks Parkway, has already jumped from producing 3 millio Aspen Participant Comment
Eight months after the previous season's cliffhanger, 350 million people around the world tuned in to watch Dallas to find out who shot J.R. Ewing, the character fans loved to hate. Cambrex has entered into an agreement to acquire Avista Pharma Solutions for $252 million. The East Rutherford-based maker of pharmaceutical ingredients said the deal will allow it to enter the early stage small molecule development and testing se The latest clinical results for Pfizer and Merck KGaA's cancer drug Bavencio won't help the companies make up ground in immuno-oncology, showing the checkpoint inhibitor failed to beat out chemotherapy in tough-to-treat forms of ovarian cancer. In Seven African-American women who work at the Charles River Labs facility in Charleston, S.C., have filed a lawsuit in the U.S. District Court in South Carolina alleging that the CRO ignored "several discrimination, harassment and retaliation compl A U.S. Patent Application for a "Mixing Device for Mixing the Content of a Bioreactor, Comprising a Synchronization Mechanism" was published by Sartorius Stedim on November 15th, 2018. The present invention relate Participant Comment Aspen Participant Comment
Before the marriage, Phili, former prince of Greece and Denmark, renounced his titles. Wed in a lavish ceremony at Westminster Abbey in London, they received 2,300 wedding gifts from around the world. CASI Pharmaceuticals has announced that it has entered into a framework agreements to build a state-of-the-art manufacturing site strategically located in the Wuxi Huishan Economic Development Zone in Jiangsu Province, China. The facility will be Roche's Genentech is to build on its existing partnership with T cell receptor (TCR) specialists Immunocore, and this time around the companies take aim at a certain protein type found in many solid tumors. That protein is known as MAGE-A4 and Imm The U.S. FDA has expanded the approved use of Adcetris injection in combination with chemotherapy for certain types of peripheral T-cell lymphoma (PTCL). This is the first FDA approval for treatment of newly diagnosed PTCL, and the agency used a n Participant Comment Aspen Participant Comment
Considered to be one of the greatest films ever made, One Flew Over the Cuckoo's Nest wone all five major Academy Awards (Best Picture, Actor in a Lead Tole, Actress in a Lead Role, Director, and Screenplay). The FDA approved a label expansion for Adcetris less than two weeks after Seattle Genetics submitted the sBLA. The agency said Adcetris is the first U.S.-approved treatment for newly diagnosed peripheral T-cell lymphoma (PTCL), and the second drug Lilly is understood to be considering the sale of a portfolio of off-patent drugs in China as the leading biopharma seeks to raise cash amid a push into higher-growth products. According to reports, Lilly is working with advisers to gauge interest Sartorius Stedim and Lonza have announced that they have modified their current agreement for supply of cell culture media by mutual accord. The agreement, signed in 2012, gave Sartorius exclusive sales and marketing rights for certain cell cultur For the sake of clarity I'm going to go ahead and assume that by single-use you do not mean glass and by rigid wall you are not looking at bags. That being the case, the only option of which I'm aware is the BioBLU family of bioreactors from Eppen
1916 Jack London dies
Mylan Receives Warning Letter from FDA for Manufacturing Failings at Key Plant
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Protein Purification Using Bis-Tris Buffer
Seqirus Breaks Ground on $140M Manufacturing Site Expansion
Previous Poll Results (%)
When talking about politics with people you disagree with, do you find you have more in common or less in common politically than you thought?
I Don’t Want Children – Stop Telling Me I’ll Change My Mind
1980 Millions tune in to find out who shot J.R.
Cambrex to Acquire Avista Pharma Solutions for $252M
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Crocodiles Cannot Die of Old Age
Mixing Device for Mixing the Content of a Bioreactor, Comprising a Synchronization Mechanism
Which of these approaches would you prefer for bubble detection in your bioprocess?
Why? %
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Previous Poll Results (%)
Do you find talking about politics with people you disagree with to be stressful/frustrating or interesting/informative?
How My Dad’s Dementia Changed My Idea of Death and Life
1947 Princess Elizabeth marries Philip Mountbatten
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The Earth has Another Continent Known as Zealandia
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Is the ability to detect bubbles in your bioprocess flow path a ‘must have’ or a ‘nice to have’?
Why? %
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Previous Poll Results (%)
How did you pay for the majority of you college expenses?
How the Military Fights Climate Change
1975 One Flew Over the Cukoo’s Nest debuts
FDA Approves Second Drug Using Real-Time Review
Eli Lilly Considering Sale of China Assets to Raise Cash
Sartorius Stedim and Lonza Modify Relationship for Supply of Cell Culture Media
Crocodiles Can Jump Vertically
I’m considering going with a rigid wall bioreactor, single use, but need to be able to scale-up to at least 50L in total volume. What are my options?
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